Andrographis paniculata (Sinta) contains diterpene compounds called andrographolide, 14-deoxyandrographolide, and 14-deoxy-11, 12-didehydroandrographolide. Studies show that andrographolide is the major component of Andrographis extracts. Andrographolide is the main bioactive constituent that has anticancer activity tested on diverse human cancer cells. Research also suggests that the extract possesses hepatoprotective, antiviral, antimicrobial, anti-parasitic, antihypertensive, antihyperglycemic, immunomodulatory, and antiproliferative properties.

King-of-bitters/Sinta

Other Names: 
Andrographis, King of Bitters
Other Traditional Medicinal Uses: 
    • Antioxidant
    • Anti-inflammatory
    • Antihypertensive
    • Antihyperglycemic/Anti-diabetic
    • Antipyretic
    • Immunobooster
    • Antibacterial
    • Antifungal
    • Antiviral
    • Hepatoprotective
    • Cardioprotective
    • Antidiarrheal
    • Choleretic
    • Hypocholesterolemic
    • Adaptogenic
    • Treats common cold and flu
    • Gastric tonic
    • Antithrombotic
    • Treats certain skin diseases (boils,scabies)
    • Anti-cancer/Anti-tumor
References: 
  • https://pubchem.ncbi.nlm.nih.gov/compound/Andrographolide http://www.webmd.com/vitamins-supplements/ingredientmono-973-andrographis.aspx?activeingredientid=973&activeingredientname=andrographis
  • http://s3.amazonaws.com/academia.edu.documents/32141367/Andrographis_paniculata.pdf?AWSAccessKeyId=AKIAIWOWYYGZ2Y53UL3A&Expires=1497431710&Signature=UlTGf6fsuhz%2FOhTa%2FVV6jMWKgQ4%3D&response-content-disposition=inline%3B%20filename%3DAndrographis_paniculata.pdf https://examine.com/supplements/andrographis-paniculata/ http://www.sciencedirect.com/science/article/pii/S0378874104001060
  • http://onlinelibrary.wiley.com/doi/10.1046/j.1440-1681.2000.03253.x/full http://onlinelibrary.wiley.com/doi/10.1002/ptr.1765/abstract
  • https://www.researchgate.net/profile/John_Babish/publication/230068153_A_phase_I_trial_of_Andrographolide_in_HIV_positive_patients_and_normal_volunteers/links/0c96053a88e9097e66000000/A-phase-I-trial-of-Andrographolide-in-HIV-positive-patients-and-normal-volunteers.pdf https://www.drugs.com/npp/andrographis.html
  • http://www.sciencedirect.com/science/article/pii/S0367326X0300159X http://www.tandfonline.com/doi/abs/10.1080/08923970600626007
  • http://s3.amazonaws.com/academia.edu.documents/41502542/Current_Science_Bangalore_76_833-835.pdf?AWSAccessKeyId=AKIAIWOWYYGZ2Y53UL3A&Expires=1497431406&Signature=%2FhiNoJ42J%2FUtNJaI0X%2FhoepI13Y%3D&response-content-disposition=inline%3B%20filename%3DThe_Use_of_RAPD_in_Detecting_Genetic_Var.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032030/
  • https://www.ncbi.nlm.nih.gov/pubmed/14641821 https://www.herbal-supplement-resource.com/andrographis-herb.html