Phyllanthus niruri (Sampa-sampalukan) consists of active phytochemicals, flavonoids, alkaloids, terpenoids, lignans, polyphenols, tannins, coumarins and saponins.

Niruside, a specific compound present in Sampa-sampalukan, was identified to have HIV-1 Reverse transcriptase inhibition thus making it a potential anti-HIV agent. Another compound also present in Sampa-sampalukan is ellagic acid which possesses aldose reductase inhibition making it useful for diabetes. Other constituents like rutin and quercetin have anti-inflammatory and analgesic activity while geraniin has anti-allergy and ACE inhibitory activity.

Studies showed that Sampa-sampalukan extract has antioxidant, hepatoprotective, gastroprotective, anti-hepatits B, anti-HIV, anti-urolithiatic, antidiabetic, anti-carcinogenic, and lipid lowering activities.


Other Names: 
Chanca piedra, Stone breaker, Gale of the wind
Other Traditional Medicinal Uses: 
    • Antioxidant
    • Anti-inflammatory
    • Anti-urolithiatic
    • Antihypertensive
    • Antihyperglycemic
    • Antihyperlipidemic
    • Hepatoprotective
    • Antiviral
    • Antihyperuricemic
    • Antipyretic
    • Analgesic
    • Stomach tonic
    • Antispasmodic/Smooth muscle relaxant
    • Cough and cold remedy
    • Antiplasmodial/Antimalarial
    • Reduces cancer risk/Anti-tumor